FIGURE 1.

Evading neutrophil extravasation to the infection site. Mechanisms by which S. aureus evades the steps in neutrophil extravasation. Neutrophils start to roll on the activated endothelium, which leads to firm adhesion and subsequently to transmigration through the endothelium. Red boxes indicate staphylococcal proteins, and blue boxes indicate host proteins. Abbreviations: PSGL-1, P-selectin glycoprotein 1; SSL, staphylococcal superantigen-like protein; ICAM-1, intracellular adhesion molecule 1; Eap, extracellular adherence protein; SElX, staphylococcal enterotoxin-like X. The figure was adapted from Servier Medical Art.