TABLE 1.

Abbreviations of staphylococcal immune evasion proteins, what they evade, and on which MGE or paralogous gene cluster they are located^a

Abbreviation	Full name	Evades processb	MGEc
Aur	Aureolysin	III, V
CHIPS	Chemotaxis inhibitory protein of Staphylococcus	II	IEC-1/ɸSa3
Can	S. aureus collagen adhesion	III
Eap and EapH	Extracellular adherence protein and extracellular adherence protein homologue	I, V
Ecb	Extracellular complement-binding protein	III	IEC-2
Efb	Extracellular fibrinogen-binding protein	III	IEC-2
FLIPr	FPR2 inhibitory protein	II	IEC-2
Hla	Hemolysin-alpha	V
Hlg	Hemolysin-gamma	V
LukS-PV	Panton Valentine leukocidin	V	ɸSa2
Luk-AB	Leukocidin AB	V
Luk-DE	Leukocidin DE	V
Nuc	Nuclease	IV
PSMs	Phenol-soluble modulins	V
Sags	Superantigens	V	IEC1, SaPIn1, vSaβd
SAK	Staphylokinase	III, V	IEC-1/ɸSa3
Sbi	Staphylococcal binding of IgG	III
SCIN	Staphylococcal complement inhibitor	III	IEC-1/ɸSa3
ScpA	Staphopain A	II
SdrE	Surface-associated serine-aspartate repeat protein E	III
SelX	Staphylococcal enterotoxin-like X	I
SpA	Staphylococcal protein A	III
SPIN	Staphylococcal peroxidase inhibitor	V	vSaαd
SSL	Staphylococcal superantigen-like 1-11	I, II, III	vSaαd
SSL	Staphylococcal superantigen-like 12, 13, 14	I, II, III	vSaβd

^a MGE, mobile genetic element.

^b The innate immune mechanisms that are inhibited: I, neutrophil extravasation; II, priming, chemotaxis, and activation of neutrophils; III, opsonization and phagocytosis; IV, NET formation; V, bacterial killing by neutrophils.

^c IEC, immune evasion cluster; SaPI, staphylococcal pathogenicity island.

^d vSaα and vSaβ are clusters of paralogous genes that have evolved in situ, are nearly universally conserved in S. aureus, and are not MGEs.