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. 2024 Nov 25;46:25. doi: 10.1186/s41021-024-00319-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Effect of N-acetyl-l-cysteine (NAC) on micronucleus (MN) induction in CHL/IU and BEAS-2B cells exposed to β-damascone (β-Dam) or mitomycin C (MMC). The frequency of micronucleated cells (% MN frequency) was measured after 27 h of exposure to β-Dam or MMC in CHL/IU cells (a, c). The same measurement was also conducted in BEAS-2B cells (b, d) after 24 h of exposure to each chemical. Solid and dotted lines represent the values obtained with or without NAC co-treatment, respectively. Closed and open symbols or bars represent the values obtained at concentrations causing more than and less than 40% relative population doubling, respectively. Each result represents the mean and standard error of the mean for three independent experiments. #Significantly different from the solvent control group (P < 0.05, Dunnett's test). * Significantly different from the solvent control group (P < 0.05, Welch's t-test)