Table 2. Comparison of BCVA, visual field MD scores, and depression scores and severity between the groups.
|
Control, n=60 |
RP, n=74 |
Total, n=134 |
p |
|
|
BCVA (Snellen decimal) |
- |
|||
|
Median (IQR) |
1.00 (1.00, 1.00) |
0.10 (0.05, 0.25) |
0.65 (0.08, 1.00) |
|
|
Range |
1.00, 1.00 |
0.001, 0.90 |
0.001, 1.00 |
|
|
BCVA quartile, decimal |
- |
|||
|
0.001-0.05 |
0 (0) |
36 (49) |
36 (27) |
|
|
>0.05-0.70 |
0 (0) |
35 (47) |
35 (26) |
|
|
>0.70-1.00 |
0 (0) |
3 (4.1) |
3 (2.2) |
|
|
1.00 (normal) |
60 (100) |
0 (0) |
60 (45) |
|
|
MD (dB) |
0.0011 |
|||
|
Median (IQR) |
-3 dB (-3, -4) |
-28 dB (-18, -32) |
-6 dB (-3, -30) |
|
|
Range |
-2, -5 dB |
-1, -34 dB |
-1, -34 dB |
|
|
MD Quartile*, dB |
n=45 |
n=105 |
0.0012 |
|
|
-0.83 to -3.00 |
40 (67) |
3 (6.6) |
43 (41) |
|
|
-3.00 to -5.63 |
20 (33) |
4 (8.8) |
24 (23) |
|
|
-5.63 to -30.2 |
0 (0) |
21 (46.6) |
21 (20) |
|
|
-30.2 to -34.0 |
0 (0) |
17 (37.7) |
17 (16) |
|
|
Total BDI score |
0.0011 |
|||
|
Median (IQR) |
12 (8, 17) |
19 (13, 25) |
16 (11, 22) |
|
|
Range |
1, 28 |
0, 44 |
0, 44 |
|
|
Depression severity |
0.0012 |
|||
|
None (BDI 0-13) |
19 (32) |
7 (9.5) |
26 (19) |
|
|
Mild (BDI 14-19) |
26 (43) |
22 (30) |
48 (36) |
|
|
Moderate (BDI 20-28) |
15 (25) |
31 (42) |
46 (34) |
|
|
Severe (BDI 29-63) |
0 (0) |
14 (19) |
14 (10) |
*Visual field results from 29 patients with low reliability or poor fixation were excluded from the analysis. 1Mann-Whitney U test, 2Fisher’s exact test. BCVA: Best corrected visual acuity, MD: Mean deviation, RP: Retinitis pigmentosa, IQR: Interquartile range, dB: Decibel, BDI: Beck Depression Index