Table 1. Demographic characteristics, clinical and laboratory evaluation of patients with craniopharyngioma at presentation.
Demographic characteristics | |
Patients (n) |
152 |
Age at the time of diagnosis (year) |
9.1±3.6 |
Sex |
|
Female (n) |
64 (42%) |
Male (n) |
88 (58%) |
Height SDS |
-1.9±1.5 |
Short stature at diagnosis |
|
Female (n) |
19 (height SD: -2.9±0.14) |
Male (n) |
20 (height SD: -3.1±0.20) |
BMI SDS |
0.7±1.6 |
Obesity at diagnosis |
|
Female (n) |
10 (BMI SD: 2.6±0.16) |
Male (n) |
25 (BMI SD: 2.7±0.15) |
Pubertal status |
|
Prepubertal (n) |
110 (72%) |
Pubertal (n) |
42 (28%) |
Symptoms at diagnosis | |
Headache |
104 (68%) |
Had vision problems |
|
Reduced visual acuity |
52 (34%) |
Restricted vision |
7 (5%) |
Diplopia |
2 (1%) |
Nystagmus |
2 (1%) |
Impaired growth |
23 (15%) |
Nausea and vomiting |
11 (7%) |
Neurological symptoms |
14 (9%) |
Pubertal problems |
4 (3%) |
Hormone deficiencies in patients | |
TSH deficiency |
121 (79%) |
ACTH deficiency |
106 (69%) |
Central diabetes insipidus |
95 (62.5%) |
GH deficiency |
83 (54.6%) |
Gonadotropin deficiency |
63 (41%) |
Prolactin level (n=137) |
|
- Elevated |
48 (35%) |
- Normal |
68 (49.6%) |
- Low |
23 (16.7%) |
BMI SDS: body mass index standard deviation (SD) score, ACTH: adrenocorticotropic hormone deficiency, TSH: thyroid-stimulating hormone, GH: growth hormone