Figure 1.

Genetic features of spontaneous fosfomycin-resistant P. entomophila isolates: (A) Distribution of mutation types as detailed in Table 1, categorized by deletions, insertions, missense, nonsense, and absence of mutations. Different shades of the same color represent distinct mutations within the same category; (B) Mutation mapping along the open reading frames of the glpT and phoU genes. Bar height indicates the abundance of mutations at each position. As shown in Table 1, all mutations occur only once, except the deletion at codon 423 (which appears five times. Note that mutations are scattered along the glpT sequence, consistent with their presumed loss-of-function nature. The colors correspond to those in panel (A).