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Luciferase assays in SW480 colon tumor cells showing that the E3 promoter transactivates the Tcf-E2 promoter. + E3, wild-type E3 promoter; − E3, mutant E3 promoter; wt E2, wild-type E2 promoter; 2, 3, or 4 Tcf E2, E2 promoter containing 2, 3, or 4 Tcf sites. The assays were performed in the presence of cotransfected E1A.
