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(A) Multiple DNAzyme-powered biosensor for single-molecule monitoring of FTO [127]. (B) Bidirectional strand displacement-driven single-molecule biosensor for simultaneously measuring hAAG and hSMUG1 [128]. (C) Single-molecule biosensor for the measurement and imaging of UDG activity based on CHA-induced FRET [138]. (D) AuNP-based single-molecule biosensor for monitoring APOBEC3A activity by utilizing ERA reaction [144].
