Table 1.
Experiments, survival times, experimental groups, and respective treatments. VRA: ventral root avulsion; VRR: ventral root reimplantation; DMEM: Dulbecco’s Modified Eagle Medium, a control for cell therapy; DMF: dimethyl fumarate 15 mg/kg; AT-MSC: adipose tissue-derived mesenchymal stem cells; and BM-MSC: bone marrow-derived mesenchymal stem cells.
Experiments | Groups | ||
---|---|---|---|
Experiment I (4 weeks) |
DMEM (N = 5) |
AT-MSC (N = 6) |
BM-MSC (N = 5) |
Experiment II (12 weeks) |
VRR (N = 6) |
VRR + AT-MSC (N = 5) | VRR + DMF + AT-MSC (N = 5) |
Experiment III (1 week) |
No lesion (N = 5) |
VRA (N = 5) |
VRR (N = 5) |
VRR + DMF (N = 5) |
VRR + AT-MSC (N = 5) | VRR + DMF + AT-MSC (N = 5) |