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H2S-producing enzymes cystathionine-β-synthase (CBS) (upper panel, n = 12) and cystathionine-γ-lyase (CSE) (lower panel, n = 12) in the paraventricular nucleus of the hypothalamus. Representative images (left panel) and quantification of immunohistochemical staining as positive tissue [pink, %] (right panel). f: female (open circles), m: male (solid squares), ELS: early life stress (red symbols), control (blue symbols).
