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. 2024 Nov 17;12(11):2629. doi: 10.3390/biomedicines12112629

Figure 5.

Figure 5

Effects of experimental periodontitis on the inflammatory status of the serum and systemic organs. Myeloperoxidase (MPO) activity in the serum of rats (a). Results represent the means ± SEM of three samples. Inflammatory mediator production (TNF-α, IL-6, IL-1β) in the serum of the rats (b). ELISA kits were employed to detect the protein levels of the inflammatory cytokines. Results represent the means ± SEM of three samples. H&E staining of major organs (heart, liver, spleen, lung, and kidney) in experimental rats (c). No obvious damage was observed in the visceral organs (n = 6/group). Statistical analysis was performed with one-way ANOVA. ns, no significance. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.