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. 2024 Nov 19;13(11):949. doi: 10.3390/biology13110949

Figure 2.

Figure 2

IKE and Eto combined treatment blocked the accumulation of MDSCs in vivo. Flow cytometry detected the percentages of MDSCs (CD45+CD11b+Gr-1+) and fold change of indicated treatment relative to control group (a), MFI of ROS and fold change of indicated treatment relative to control group (b), MFI of fatty acid uptake and fold change of indicated treatment relative to control group (c), MFI of lipid droplets and fold change of indicated treatment relative to control group (d), MFI of mitochondrial superoxide anions and fold change of indicated treatment relative to control group (e), and MFI of mitochondrial mass and fold change of indicated treatment relative to control group (f) in spleen MDSCs of MC38-bearing mice on day 16. Results from three independent experiments (a–f). Statistical analysis was performed using one-way ANOVA (a–f). Data are expressed as means ± SEM (n = 3). * p < 0.05 and **** p < 0.0001; ns, no significant difference.