Table 3.

Association between personal and family history of malignancies and GPV detection in patients with PDAC (n = 179).

	OR	95% (CI)	p Value
Personal history of other malignances (any)	3.5	(1.1–11.6)	0.03
Family history of other malignancies (first- or second-degree)
Breast	8.5	(2.6–26.6)	<0.001
Prostate	3.6	(0.87–15.8)	0.06
Pancreas	3.7	(1.08–13.6)	0.044
Ovarian	3.6	(0.69–19.2)	0.15
Colorectal	1.3	(0.28–6.4)	0.66
Melanoma	0.98	(0.16–6.6)	0.70
Gastric	0.62	(0.076–4.993)	0.65
Clinical criteria for HBOC	32.8	(7.1–150.9)	<0.0001

GPV, germline pathogenic variants; PDAC, pancreatic duct adenocarcinoma; OR, odds ratio; CI, confidence interval, HBOC: hereditary breast and ovarian cancer syndrome.