| 5-mC | 5-methylcytosine |
| ABH | AlkB homologs |
| ADC | Apparent diffusion coefficient |
| αKG | α-ketoglutarate |
| AML | Acute myeloid leukemia |
| ATF | Activating transcription factor |
| ATM | Ataxia-telangiectasia-mutated |
| ATRX | Alpha thalassemia/mental retardation syndrome X-linked gene |
| BBB | Blood–brain barrier |
| BCAA | Branched-chain amino acids |
| BCAT (1/2) | Branched-chain aminotransferase (1 or 2) |
| BEAMing | Beads, emulsion, amplification, magnetics |
| CPE | Carboxypeptidase |
| CDC20 | Cell division cycle 20 |
| cfDNA | Cell-free circulating DNA |
| CHD (3-5) | Chromodomain helicase DNA binding protein (3-5) |
| CRISPR | Clustered regularly interspaced short palindromic repeats |
| CSF | Cerebral spinal fluid |
| D-2-HG | D-2-Hydroxyglutarate |
| ddPCR | Digital droplet PCR |
| DDR | DNA damage repair |
| DBC1 | Deleted in breast cancer 1 |
| DSB | Double-stranded break |
| DSC | Dynamic susceptibility contrast-enhanced MRI |
| DTI | Diffusion tensor imaging |
| DWI | Diffusion-weighted MRI |
| EN2 | Engrailed 2 |
| EGFR | Epidermal growth factor receptor |
| FDA | Food and drug administration |
| FFPE | Formalin-fixed paraffin-embedded tissue |
| FRET | Fluorescence resonance energy transfer |
| FTO | Fat mass and obesity-associated protein |
| G-CIMP | Glioma CpG island methylator phenotype |
| GBM | Glioblastoma multiforme |
| GC–MS | Gas chromatography–mass spectroscopy |
| H&E | Hematoxylin and Eosin |
| HDAC | Histone deacetylase |
| HIF | Hypoxia-inducible factor |
| IDH | Isocitrate dehydrogenase |
| JmjC | Jumonji-C |
| KDM | Histone lysine demethylase |
| L-2-HG | L-2-Hydroxyglutarate |
| LAMP | Loop-mediated isothermal amplification |
| LC–MS | Liquid chromatography–mass spectroscopy |
| LDH (A/B) | Lactate dehydrogenase A or B |
| LNA | Locked nucleic acid |
| m6A | N6-methyladenosine |
| MAPK | Mitogen-activated protein kinase |
| MCT | Monocarboxylate transporters |
| MGMT | Methyl guanine methyl transferase |
| MRI | Magnetic resonance imaging |
| MRS | Magnetic resonance spectroscopy |
| MTT | Mean transit time |
| NAMPT | Nicotinamide phosphoribosyltransferase |
| nCATS | Nanopore Cas9 targeted sequencing |
| NGS | Next generation sequencing |
| NuRD | Nucleosome remodeling |
| ONT | Oxford nanopore technology |
| PARP | Poly(ADP) ribose |
| PDB | Protein data bank |
| PFKP | Phosphofructokinase platelet |
| PHD | Prolyl hydroxylase |
| PNA | Peptide nucleic acid |
| PWI | Perfusion weighted MRI |
| PYCR1 | Proline 5-carboxylase reductase 1 |
| qRT-PCR | Quantitative real-time PCR |
| rCBF | Relative cerebral blood flow |
| rCBV | Relative cerebral blood volume |
| RNAseq | RNA sequencing |
| SNV | Single nucleotide variant |
| ssRNAseq | Single-cell RNA sequencing |
| STAT | Signal transducer and activator of transcription |
| T2-FLAIR | T2 fluid-attenuated inversion recovery |
| TERT | Telomerase reverse transcriptase |
| TET | Ten-eleven translocation |
| TMZ | Temozolomide |
| VAF | Variant allele frequency |
| VIM | Vimentin |
| WHO CNS5 | World Health Organization central nervous system 5 |
| WASF3 | Wiskott–Aldrich syndrome protein family |
| ZMYND8 | Zinc finger MYND-type containing 8 |