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. 2024 Nov 4;12(11):2519. doi: 10.3390/biomedicines12112519

Figure 3.

Figure 3

Panels A-H represent daily average salivary interleukin levels in pg/mL at Time 1 (waking) and Time 2 (30 min post waking) during repeated acute stress. Error bars represent the SEM. Results of pairwise comparisons between average cytokine values at each time point are shown by the compact letter display. Two means with the same letter are not significantly different at the 0.05 level. All interleukins exhibited significant decreases in average salivary concentration from Time 1 to Time 2 in all days of the sampling period. IL-1a, IL-8 Il-15, IL-18, and IL-1RA, p < 0.0001. IL-6 Day 1, p = 0.0014; Day 2, p = 0.0124; Day 3, p = 0.0003; Day 4, p < 0.0001. IL-10 Day 1, p = 0.003; Day 2, p = 0.0056; Day 3, p = 0.0086; Day 4, p = 0.0098. IL-1B Day 1, p = 0.0001; Days 2–4, p < 0.0001. (a) IL-1a (n = 79), (b) IL-6 (n = 79), (c) IL-8 (n = 79), (d) IL-10 (n = 79), (e) IL-15 (n = 79), (f) IL-18 (n = 79), (g) IL-1β (n = 40), (h) IL-1RA (n = 79).