Table 5.
A comparison of sarcoma radiotherapy and proton beam therapy side-effects and patient-reported outcome measures.
| PROM | PROM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Site-Specific Side-Effects | EORTC-QLQ-C30 | PROMIS-29 | EORTC-QLQ-CR29 | Site-Specific Side-Effects | MHQ | FAOS | TESS-UE | TESS-LE | ||
| PELVIC SARCOMA | Tiredness | Y | Y | LIMB SARCOMA | Tiredness | Y | Y | |||
| Increased urinary frequency or urgency | Y | Hair loss | ||||||||
| Increased bowel frequency or urgency | Y | Skin reaction | ||||||||
| Dysuria | Skin itching | |||||||||
| Pain or discomfort | Y | Y | Y | Pain or discomfort | Y | Y | Y | Y | ||
| Looser stools | Y | Change in skin colour | ||||||||
| Skin reaction | Change in skin texture | |||||||||
| Skin itching | Joint stiffness | Y | Y | Y | Y | |||||
| Nausea | Y | Weakness or reduced motor function | Y | Y | Y | Y | ||||
| Vomiting | Y | Swelling or lymphoedema | Y | |||||||
| Urinary incontinence | Y | Tingling or numbness | Y | |||||||
| Faecal incontinence | Y | Loss of appetite | ||||||||
| Blood in stool or urine | Y | |||||||||
| Early menopause | ||||||||||
| Swelling or lymphoedema | ||||||||||
| Hair loss | Y | |||||||||
| Vaginal stenosis | Y | |||||||||
| Ability to achieve and maintain erections | Y | |||||||||
C30—General cancer module; CR29—Colorectal module; EORTC—European Organisation for Research and Treatment of Cancer; FAOS—Feet and Ankle Outcome Score; LE—Lower extremity; PROMIS—Patient-Reported Outcomes Measurement Information System; QLQ—Quality of Life Questionnaire; MHQ—Michigan Hand Outcomes Questionnaire; TESS—Toronto Extremity Salvage Score; UE—Upper Extremity.