Table 6.
A comparison of prostate radiotherapy side-effects and patient-reported outcome measures.
| PROM | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Site-Specific Side-Effects | EORTC-QLQ-C30 | EORTC-QLQ-PR19 | EORTC-QLQ-PR25 | EPIC | EPIC-26 | SF-12 | SF-36 | FACT-P | Hoffman et al. [21] | UCLA PCI | SWOG-QoL | EQ-5D-5L | HFR-DIS | IPSS | IIEF-5 | ICIQ-UI SF | PROMIS-Fatigue |
| Tiredness | Y | Y | Y | Y | Y | Y | Y | Y | |||||||||
| Increased urinary frequency or urgency | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | |||||||
| Increased bowel frequency or urgency | Y | Y | Y | Y | Y | Y | Y | ||||||||||
| Dysuria | Y | Y | Y | Y | Y | Y | Y | ||||||||||
| Pain or discomfort | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | |||||||
| Looser stools | Y | Y | Y | Y | Y | Y | |||||||||||
| Skin reaction | Y | ||||||||||||||||
| Tenesmus | Y | ||||||||||||||||
| Blood in stool or urine | Y | Y | Y | Y | Y | ||||||||||||
| Urinary incontinence | Y | Y | Y | Y | Y | Y | Y | Y | Y | ||||||||
| Faecal incontinence | Y | Y | Y | Y | Y | ||||||||||||
| Change in ejaculate | Y | Y | |||||||||||||||
| Ability to achieve and maintain erections | Y | Y | Y | Y | Y | Y | Y | Y | |||||||||
| Loss of orgasm | Y | Y | Y | Y | Y | Y | |||||||||||
| Swelling or lymphoedema | Y | Y | |||||||||||||||
| Hair loss | Y | ||||||||||||||||
C30—General cancer module; EORTC—European Organisation for Research and Treatment of Cancer; EPIC—Expanded Prostate Cancer Index Composite; EQ—EuroQoL group; FACT—Functional Assessment of Cancer Therapy; HFR-DIS—Hot-Flash-Related Daily Interference Scale; ICIQ-UI SF—International Consultation on Incontinence Questionnaire—Urinary Incontinence Short Form; IIEF-5—International Index of Erectile Function; IPSS—International Prostate Symptom Scale; PR-19—Prostate module; PR-25—updated Prostate module; PROMIS—Patient-Reported Outcomes Measurement Information System; QLQ—Quality of Life Questionnaire; SF—Short-form survey; SWOG-QoL—South Western Oncology Group Quality of Life Questionnaire; UCLA-PCI—University of California, Los Angeles Prostate Cancer Index.