Table 1.
Total (n = 1503) |
Non-T2DM (n = 986) |
T2DM (n = 517) |
p | |
---|---|---|---|---|
Age (years) † | 48.10 ± 14.85 | 45.11 ± 14.95 | 53.81 ± 12.88 | <0.001 a |
Male | 48.4% | 49.3% | 46.6% | 0.352 b |
BMI (kg/m2) † | 29.39 ± 6.59 | 29.41 ± 7.23 | 29.355 ± 5.16 | 0.854 a |
Waist circumference (cm) † | 95.83 ± 12.46 | 95.41 ± 11.75 | 96.50 ± 13.54 | 0.469 a |
Hypertension | 42.4% | 33.9% | 58.6% | <0.001 b |
Diabetes | 34.4% | |||
Triglyceride (mg/dL) † | 159.46 ± 100.72 | 156.62 ± 102.69 | 164.89 ± 96.71 | 0.129 a |
HDL-CROL (mg/dL) † | 48.06 ± 14.77 | 49.00 ± 14.56 | 46.27 ± 15.00 | 0.001 a |
Cholesterol (mg/dL) | 124.39 ± 50.58 | 127.54 ± 47.84 | 118.12 ± 55.16 | 0.004 a |
Albumin (mg/dL) | 4.33 ± 0.44 | 4.35 ± 0.42 | 4.29 ± 0.46 | 0.007 a |
Glucose (mg/dL) † | 113.90 ± 35.59 | 99.45 ± 16.10 | 141.41 ± 45.07 | <0.001 a |
AST (IU/L) † | 51.54 ± 35.39 | 47.74 ± 33.87 | 58.79 ± 37.09 | <0.001 a |
ALT (IU/L) † | 73.63 ± 58.89 | 71.19 ± 60.20 | 78.29 ± 56.07 | 0.023 a |
AST/ALT † | 0.8697 ± 0.4423 | 0.8650 ± 0.4634 | 0.8786 ± 0.3993 | 0.555 a |
Platelets (×109/L) † | 236.65 ± 72.67 | 246.55 ± 70.32 | 217.78 ± 73.41 | <0.001 a |
FIB-4 index † | 1.58 ± 1.47 | 1.32 ± 1.24 | 2.07 ± 1.73 | <0.001 a |
NAFLD fibrosis score † | −1.82 ± 1.67 | −2.46 ± 1.39 | −0.58 ± 1.45 | <0.001 a |
Steatosis | 1.39 ± 1.01 | 1.24 ± 1.03 | 1.74 ± 0.86 | <0.001 a |
Inflammation | 1.11 ± 0.99 | 0.91 ± 0.96 | 1.56 ± 0.90 | <0.001 a |
Fibrosis | 285 (19.0%) | 130 (13.2%) | 155 (30.0%) | <0.001 b |
Prevalence of ≥F2 | 1218 | 856 | 362 | |
Prevalence of ≥F3 | 285 | 130 | 155 |
Data are expressed as number (percent). † Data are shown as mean ± standard deviation. Abbreviations: AST, aspartate transaminase; ALT, alanine transaminase; BMI, body mass index; HDL, high-density lipoprotein; NAFLD, non-alcoholic fatty liver disease; a Student’s t-test; b Chi-square test.