Figure 2.

Luciferase activities of T or C allele of rs1231760 in RGS2 in A549 cells with or without dexamethasone stimulation. To compare the transcriptional activities between the T and C alleles of rs1231760 in RGS2, a Firefly reporter plasmid containing the T or C allele of rs1231760 and GR binding sequence and Nanoluc luciferase plasmid were cotransfected into A549 cells. The Firefly luciferase activity was normalized by that of Nanoluc. Data are presented as the mean ± SD from five independent experiments. *** p < 0.001, one-way ANOVA with Tukey’s test.