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LMP1TRADD delays the onset of replicative senescence of MEF. Replicative senescence was examined in MEF infected with retroviruses carrying genes for LNSX, LMP1, or LMP1TRADD at the indicated passage numbers with SA-β-Gal staining (39). The mean and standard deviation of the percentage of blue cells were determined in three independent areas with about 300 cells each.
