Figure 7.

Differential expression of Group_D_NEUT_MAST. Scatterplot of the first two principal components (Dim1 and Dim2) of the RNA-seq (A) and proteomic samples (C), clustered according to their gene and protein expression; in parenthesis: the original variance explained by each principal component. The larger symbols represent group means. Volcano plots of the differentially expressed genes (B) and proteins (D) identified between Group_D_NEUT_MAST and the control group. The green dots denote molecules with an absolute log2-fold change of >1. The blue dots denote genes with an FDR of ≤0.05, and the red dots those with an FDR of ≤0.05 and an absolute log2-fold change of >1 (B). In the proteomic dataset, the blue dots denote those with a p-value of ≤0.05, and the red dots those with a p-value of ≤0.05 and an absolute log2-fold change of >1 (D). Finally, the grey dots denote the gene/protein expression without marked differences.