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. 2024 Nov 14;16(22):3823. doi: 10.3390/cancers16223823
ADAM17 ADAM Metallopeptidase Domain 17
ADMET Absorption–Distribution–Metabolism–Excretion–Toxicity
AGR2 Anterior gradient protein two homolog
Akt Protein kinase B
APC Anaphase-Promoting Complex
Arf/CDKN2A Cyclin-Dependent Kinase Inhibitor 2A
ATM Ataxia telangiectasia
BC Breast cancer
Bcl-2 B-Cell Lymphoma 2
BRCA2 Breast cancer 2
Cdc25 Cell division cycle 25
CDK Cyclin-Dependent Kinase
CDH1 Cdc20 homolog 1
CENP Centromere Protein
CHK2 Checkpoint kinase 2
CISR Cisplatin-resistant
CREB cAMP-Response Element Binding Protein
CTCF CCCTC-Binding Factor
CTLA4 Cytotoxic T-lymphocyte-associated protein 4
DBD DNA-binding domain
DNA Deoxyribonucleic acid
DUB Deubiquitinating enzyme
E2F Early region 2 binding factor
E2F1 Early region 2 binding factor 1
E3 Ligase E3 ubiquitin–protein ligase
eEF2K Eukaryotic elongation factor 2 kinase
EMT epithelial–mesenchymal transition
ERβ1/EGFR ErbB-1, also named epidermal growth factor receptor
ERK extracellular signal-regulated kinase
ER Estrogen
FDA Food and Drug Administration
FDI-6 Forkhead Domain Inhibitor-6
FHRE Forkhead elements
FOX Forkhead box
FOXM1 Forkhead box M1
FT-IR Fourier transform infrared spectroscopy
GATA3 GATA Binding Protein 3
GBM Glioblastoma multiforme
GLI1 Glioma-Associated Oncogene Homolog 1
H Histidine
HCC Hepatocellular carcinoma
HER2 Human epidermal growth factor receptor 2
HGF Hepatocyte growth factor receptor
HH Hedgehog
HIF1α Hypoxia-Inducible Factor 1 alpha
ITGB1 Integrin subunit beta 1
IPO Importin-7
JNK Jun N-terminal kinase
KIF20A Kinesin family member 20
LC3 Microtubule Associated Protein 1 Light Chain 3 Alpha
LC-MS Liquid chromatography–mass spectrometry
lncRNAs Long noncoding RNAs
MAPK Mitogen-activated protein kinase
MCF7 Michigan Cancer Foundation-7
Mcl-1 Myeloid Cell Leukemia 1
MD simulation Molecular dynamics simulation
MELK Maternal embryonic leucine zipper kinase
MEK Mitogen-activated protein kinase
MET Mesenchymal Epithelial Transition
miR/miRNA microRNA
MMP Matrix metalloproteinase
MRE11 Meiotic recombination 1
mRNA Messenger RNA
ncRNA Non-coding RNA
N Asparagine
NF-kB Nuclear factor kappa B
NMR Nuclear magnetic resonance spectroscopy
n-Ras Neuroblastoma rat sarcoma virus
NRD N-terminal repressor domain
NSCLC Non-small cell lung cancer
NRFM Negative regulators of FOXM1
OS Overall survival
PARP Poly (ADP-ribose) polymerase
p27/Kip1 Cyclin-Dependent Kinase Inhibitor 1B
PD1 Programmed Cell Death Protein 1
PD-L1 Programmed Cell Death Ligand 1
PVT1 Plasmacytoma variant translocation 1 gene
PLK Polo-like kinases
POI Protein of interest
PPI Protein–protein interaction
p-PKCδ Phosphoprotein kinase Cδ
PR Progesterone
PROTAC Proteolysis-targeted chimera
PTEN Phosphatase and Tensin Homolog
PTM Post-translational modification
PVT1 plasmacytoma variant translocation 1 gene
R Arginine
RAD51 RADiation sensitive protein 51
RAF Rapidly Accelerated Fibrosarcoma
Rb Retinoblastoma protein
RCM-1 Robert Costa Memorial drug-1
RFC5 Replication Factor C Subunit 5
S Serine
siRNA Small interfering RNA
SLUG Zinc finger protein SNAI2
SMAD3 Mothers against decapentaplegic homolog 3
Snail Zinc finger protein SNAI1
Sox2 SRY-Box Transcription Factor 2
SRC Src proto-oncogene
SRT-100 Solanum incanum extract
STAT3 Signal transducer and activator of transcription 3
SUMO Small Ubiquitin-like Modifier
T Threonine
TAD Transactivation domains
TMZ Temozolomide
TNBC Triple-negative breast cancer
TGF-β Transforming Growth Factor Beta 1
TP53 Tumor Protein P53
TPD Targeted protein degradation
XIAP X-linked inhibitor of apoptosis protein
XRCC1 X-ray repair cross-complementing protein 1
IBE2C Ubiquitin-conjugating enzyme E2C
U87MG Uppsala 87 Malignant Glioma
U373 Uppsala 373
USP7 Ubiquitin Specific Peptidase 7
USP21 Ubiquitin-specific protease
VEGFA Vascular endothelial growth factor A
VHL Von Hippel–Lindau syndrome
WDR5 WD repeat domain 5
WNT Wingless-related integration site
5-FU 5-fluorouracil
5-HT7 5-hydroxytryptamine