Table 6.
Variables | pStage I, II | pStage III | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate Analysis | Multivariate Analysis | Univariate Analysis | Multivariate Analysis | |||||||||
HR | 95% CI | p Value | HR | 95% CI | p Value | HR | 95% CI |
p Value |
HR | 95% CI | p Value | |
Sex | ||||||||||||
Female | 1 | 1 | 1 | 1 | ||||||||
Male | 1.731 | 1.419–2.111 | <0.001 | 1.929 | 1.567–2.376 | <0.001 | 1.236 | 0.998–1.532 | 0.053 | 1.252 | 1.006–1.558 | 0.044 |
Age (years) | ||||||||||||
<70 | 1 | 1 | 1 | 1 | ||||||||
≥70 | 4.859 | 4.059–5.817 | <0.001 | 4.159 | 3.444–5.024 | <0.001 | 1.432 | 1.165–1.759 | <0.001 | 1.206 | 0.963–1.509 | 0.103 |
Surgical procedure | ||||||||||||
Non-TG | 1 | 1 | 1 | 1 | ||||||||
TG | 2.311 | 1.923–2.777 | <0.001 | 1.722 | 1.415–2.095 | <0.001 | 1.439 | 1.176–1.760 | <0.001 | 1.376 | 1.119–1.692 | 0.002 |
Surgical approach | ||||||||||||
Laparoscopy | 1 | 1 | 1 | 1 | ||||||||
Open | 2.298 | 1.937–2.726 | <0.001 | 1.679 | 1.303–2.164 | <0.001 | 1.446 | 0.876–2.388 | 0.149 | 1.963 | 1.117–3.452 | 0.019 |
Lymph node dissection | ||||||||||||
D1+ | 1 | 1 | 1 | 1 | ||||||||
D2 | 1.526 | 1.284–1.812 | <0.001 | 0.797 | 0.621–1.023 | 0.075 | 0.590 | 0.404–0.863 | 0.006 | 0.480 | 0.314–0.734 | <0.001 |
Histological type | ||||||||||||
Differentiated | 1 | 1 | 1 | 1 | ||||||||
Undifferentiated | 0.594 | 0.499–0.707 | <0.001 | 0.957 | 0.780–1.147 | 0.631 | 0.972 | 0.783–1.205 | 0.794 | 1.140 | 0.913–1.423 | 0.249 |
Score (Prealbumin cutoff: 15) | ||||||||||||
0 | 1 | 1 | 1 | 1 | ||||||||
1 | 2.086 | 1.737–2.506 | <0.001 | 2.027 | 1.664–2.469 | <0.001 | 1.258 | 1.010–1.565 | 0.040 | 1.212 | 0.957–1.534 | 0.110 |
2 | 3.000 | 2.269–3.967 | <0.001 | 2.535 | 1.879–3.420 | <0.001 | 0.981 | 0.720–1.335 | 0.902 | 0.962 | 0.692–1.337 | 0.817 |
Postoperative complication | ||||||||||||
Absent | 1 | 1 | 1 | 1 | ||||||||
Overall complications | 1.480 | 1.212–1.808 | <0.001 | 1.250 | 1.006–1.553 | 0.044 | ||||||
Severe complications | 1.535 | 1.128–2.091 | 0.006 | 1.194 | 0.873–1.632 | 0.267 | 1.444 | 1.061–1.966 | 0.020 | 1.269 | 0.923–1.746 | 0.143 |
Adjuvant chemotherapy | ||||||||||||
Absent | 1 | 1 | 1 | 1 | ||||||||
Present | 1.848 | 1.454–2.349 | <0.001 | 1.706 | 1.313–2.217 | <0.001 | 0.520 | 0.423–0.640 | <0.001 | 0.564 | 0.453–0.701 | <0.001 |