Table 2.
Percentage Distribution of Immune Cell Subsets Analyzed by Flow Cytometry. TEMRA; Terminal effector memory T cells, NKT; Natural Killer-like T cells, NK; Natural Killer cells, MDSC; Myeloid-Derived Suppressor Cells, DC; Dendritic Cells.
| Parent | Subset/Marker | Mean Percentage (%) ± SD |
|---|---|---|
| CD45+ | Lymphocytes (SSC low FSC low) | 72.8 ± 25.2% |
| Lymphocytes | T Cells (CD3+) | 76.5 ± 14.5% |
| CD3+ T Cells | Helper T Cells (CD4+) | 42.1 ± 24.5% |
| CD4+ Th Cells | - Naïve (CD45RA+CCR7+) | 10.8 ± 11.9% |
| CD4+ Th Cells | - Central Memory (CD45RA-CCR7+) | 27.0 ± 26.6% |
| CD4+ Th Cells | - Effector Memory (CD45RA-CCR7-) | 42.4 ± 32.5% |
| CD4+ Th Cells | - TEMRA (CD45RA+CCR7-) | 7.9 ± 15.5% |
| CD4+ Th Cells | - Activated Helper T Cells (HLA-DR+) | 4.9 ± 5.5% |
| CD3+ T Cells | Cytotoxic T Cells (CD8+) | 39.2 ± 15.4% |
| CD8+ Tc Cells | - Naïve (CD45RA+CCR7+) | 13.3 ± 11.7% |
| CD8+ Tc Cells | - Central Memory (CD45RA-CCR7+) | 11.8 ± 15.1% |
| CD8+ Tc Cells | - Effector Memory (CD45RA-CCR7-) | 36.0 ± 23.4% |
| CD8+ Tc Cells | - TEMRA (CD45RA+CCR7-) | 34.8 ± 23.2 |
| CD8+ Tc Cells | - Activated Cytotoxic T Cells (HLA-DR+) | 22.7 ± 14.9% |
| CD3+ T Cells | NKT Cells (CD56+) | 8.4 ± 6.5% |
| Lymphocytes | B Cells (CD19+) | 2.3 ± 2.9% |
| CD3-CD19- | NK Cells (CD16+CD56+) | 59.4 ± 27.4% |
| CD45+ | Monocytes (SSC high FSC low) | 21.2 ± 21.0% |
| Monocytes | Classical (CD14++CD16-) | 36.3 ± 18.5% |
| Monocytes | Intermediate (CD14++CD16+) | 19.2 ± 16.0% |
| Monocytes | Non-Classical (CD14+CD16++) | 17.3 ± 20.9% |
| Monocytes | MDSCs (Lin-CD14+DRlow) | 15.1 ± 21.9% |
| Live Scatter (CD45+CD235a-CD34-) | DCs (Lin-DR+) | 2.6 ± 3.3% |