Table 1.

The proportion of differentially expressed genes considering downregulated genes, upregulated genes, and shared genes in the GO and HPO repositories.

Study	Study Type	CHD	Controls (N)	Cases (N)	DGE (N) 1	Upregulated	Downregulated	GO (N) 2	HPO (N) 3	GO + HPO
GSE196443	RNA-Seq	Trisomy 21/CHD	5	5	23	23	0	2	0	0
GSE217557	RNA-Seq	Trisomy 21/CHD	32	50	13	12	1	0	0	0
GSE36761	RNA-Seq	ToF 4	7	22	2228	727	1501	65	59	13
GSE132401	RNA-Seq	ToF 4	5	5	111	69	42	6	5	4
GSE141955	Microarray	ToF 4	6	9	35	2	33	0	0	0
GSE23959	Microarray	HLHS 5	6	10	184	130	54	9	9	2

¹ Differentially expressed genes identified. ² Gene Ontology. ³ Human Phenotype Ontology. ⁴ Tetralogy of Fallot. ⁵ Hypoplastic Left Heart Syndrome.