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. 2024 Oct 30;15(11):1402. doi: 10.3390/genes15111402

Figure 2.

Figure 2

FISH using the RARA break apart and PML/RARA dual fusion probes. (A) Interphase FISH for RARA break apart displaying a normal 2F pattern. (B) Interphase for PML/RARA dual fusion displaying an atypical abnormal pattern of 2R 1G 1F. (C) G-banded metaphase displaying a normal female karyotype. (D) Inverted DAPI image of metaphase PML/RARA FISH, with red arrows indicating PML on 15q24, a green arrow indicating RARA on 17q21, and a yellow arrow indicating a fusion. The PML::RARA gene fusion is present on a normal-appearing 17q.