ADEVs	astrocyte-derived extracellular vesicles
AIS	acute ischemic stroke
AQP4	aquaporin-4
BBB	blood–brain barrier
C	control
cat. no.	catalog number
CNS	central nervous system
CT	computed tomography
d	standardized difference
e.g.,	for example
EVs	extracellular vesicles
GDNF	glial cell line-derived neurotrophic factor
GFAP	glial fibrillary acidic protein
GLAST	glutamate aspartate transporter
IQR	interquartile range
IS	ischemic stroke
IVT	intravenous thrombolysis
kDa	kilodaltons
mRS	modified Rankin Scale
MW	molecular weight
NIHSS	National Institutes of Health Stroke Scale
Nm	nanometers
Ns	not significant
OAPs	orthogonal arrays of particles
PAGE	polyacrylamide gel electrophoresis
PVDF	polyvinylidene difluoride
RAs	reactive astrocytes
SDS	sodium dodecyl sulfate
SE	scanning electron microscopy
TE	transmission electron microscopy
TEVs	total extracellular vesicles
t-PA	tissue Plasminogen Activator