Table 5.
Imaging Features | NB (n = 24) | GNB (n = 6) | GN (n = 10) | p-Value | |||
---|---|---|---|---|---|---|---|
Total No. | % | Total No. | % | Total No. | % | ||
Multifocal disease | 0 | 0 | 0 | 0 | 0 | 0 | - |
Multiple body compartments | 1 * | 4.2 | 0 | 0 | 0 | 0 | - |
Lobulated (presence) | 22 | 91.6 | 4 | 66.7 | 5 | 50 | 0.01 |
Heterogeneous (presence) | 20 | 83.3 | 4 | 66.7 | 7 | 70 | 0.74 |
Calcifications (presence) | 6 | 25 | 1 | 16.7 | 2 | 20 | 1.0 |
Necrosis (presence) | 4 | 16.7 | 0 | 0 | 1 | 10 | 0.82 |
Predominant T1 signal | 0.53 | ||||||
Hypointense | 10 | 41.7 | 5 | 83.3 | 7 | 70 | |
Isointense | 13 | 54.2 | 1 | 16.7 | 3 | 30 | |
Hyperintense | 1 | 4.1 | 0 | 0 | 0 | 0 | |
Predominant T2 signal | 0.83 | ||||||
Hypointense | 0 | 0 | 0 | 0 | 0 | 0 | |
Isointense | 4 | 16.7 | 0 | 0 | 0 | 0 | |
Hyperintense | 20 | 83.3 | 6 | 100 | 10 | 100 | |
Contrast enhancement | 1.0 | ||||||
Homogeneous | 8 | 33.3 | 2 | 33.3 | 3 | 30 | |
Heterogeneous | 14 | 58.3 | 4 | 66.7 | 6 | 60 | |
No contrast | 2 | 8.3 | 0 | 0 | 1 | 10 | |
Image-defined risk factors (IDRFs) | 15 | 62.5 | 2 | 33.3 | 2 | 20 | 0.07 |
Vascular encasement (presence) | 10 | 41.7 | 2 | 33.3 | 2 | 20 | 0.53 |
Intraspinal invasion (presence) | 8 | 33.3 | 0 | 0 | 0 | 0 | 0.04 |
Adjacent organ infiltration (presence) | 8 | 33.3 | 0 | 0 | 0 | 0 | 0.04 |
Tracheal compression (presence) | 3 | 12.5 | 0 | 0 | 0 | 0 | 0.72 |
Metastatic disease at diagnosis (presence) | 8 | 33.3 | 0 | 0 | 0 | 0 | 0.04 |
Diffusion restriction (presence) | 24 | 100 | 6 | 100 | 6 | 60 | 0.005 |
Abbreviations: NB = neuroblastoma; GNB = ganglioneuroblastoma; GN = ganglioneuroma. * Neck–chest.