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Bacterium-stimulated production of IL-10 by PBMC at 1, 4, and 7 days. PBMC were stimulated by 100 bacteria per PBMC. Supernatants were collected at the indicated times and analyzed by ELISA. The results are representative of two experiments. Each data point is the mean of triplicate samples. By one way analysis of variance with Duncan’s post hoc test, P. endodontalis (P.e.) stimulation significantly increased IL-10 production compared to S. mutans (S.m.) at all time points (P < 0.05).
