TABLE 3.
Bactericidal activity of whole-killed UC19-specific and UC19 rTbpB-specific immune serum against heterologous isolates of NTHI
| NTHI isolate | Antigen-specific serum | Bactericidal titera |
|---|---|---|
| UC19 | Whole killed UC19 | 32–64 |
| UC19 | UC19 rTbpB | 4–8 |
| UC27 | UC19 rTbpB | NDb |
| UC28 | UC19 rTbpB | 2–4 |
| UC77 | UC19 rTbpB | ND |
| UC84 | UC19 rTbpB | ND |
| UC103 | UC19 rTbpB | ND |
a
The bactericidal titer is the reciprocal of the dilution of serum that resulted in greater than 50% killing compared to the same dilution of nonimmune serum. The range is the result of two independent experiments.
b
ND, no bactericidal activity detected.