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The effect of Mitomycin C on levels of sphingosine, S1P, and sphinganine-1-p. The ASM transfected (ASM) and control transfected (pJK) cells were treated for 48 h either with or without 3 µM mitomycin C (MMC). The results are expressed in % of the untreated control and are means ± SD (n = 3). *** p < 0.0001, ** p < 0.001, and * p < 0.05 indicate statistical significance when compared to the control group.
