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. 2024 Nov 16;25(22):12320. doi: 10.3390/ijms252212320

Table 1.

Natural and synthetic compounds and their ability to bind the mineralocorticoid receptor (MR)/glucocorticoid receptor (GR).

Compound Name Binding Receptor Origin References
11-Deoxycorticosterone MR Natural [26]
Aldosterone MR Natural [27]
Corticosterone MR/GR Natural [28]
Cortisol MR/GR Natural [29]
Cortisone MR/GR Natural [30]
Progesterone MR Natural [31]
11-oxa-Cortisol GR Synthetic [32]
11-oxa-Prednisolone GR Synthetic [32]
19-Noraldosterone MR Synthetic [33]
19-Nor-Desoxycorticosterone MR Synthetic [34]
19-Nor-progesterone MR Synthetic [35]
Beclomethasone GR Synthetic [36]
Betamethasone GR Synthetic [37]
Budesonide GR Synthetic [38]
Deoxycorticosterone acetate MR Synthetic [39]
Dexamethasone GR Synthetic [40]
Dexamethasone oxetanone GR Synthetic [32]
Eplerenone MR Synthetic [41]
Finerenone MR Synthetic [42]
Fludrocortisone MR Synthetic [43]
Hydrocortisone MR/GR Synthetic [44]
Prednisolone MR Synthetic [45]
Prednisone GR Synthetic [46]
Spironolactone MR Synthetic [41]
Triamcinolone GR Synthetic [47]
Vamorolone GR Synthetic [48]