Table 1.
Characteristics of the study subjects with monoclonal protein (MP).
| Characteristics | n = 1135 |
|---|---|
| Age (years) | 71 (18–94) |
| Sex | |
| Male | 664 (58.5%) |
| Female | 471 (41.5%) |
| Serum MP level (g/dL) | 1.84 (0.01–9.45) |
| Immunotyping distribution in serum IFE | |
| IgG-κ/IgG-λ | 337 (29.7%)/222 (19.6%) |
| IgA-κ/IgA-λ | 95 (8.4%)/70 (6.2%) |
| IgM-κ/IgM-λ | 56 (4.9%)/12 (1.1%) |
| Free κ/Free λ | 19 (1.7%)/52 (4.6%) |
| Biclonal | 15 (1.3%) |
| Technical error | 2 (0.2%) |
| Only in urine | 54 (4.8%) |
| Not tested | 201 (17.7%) |
| Disease categorization | |
| Lymphoplasmacytic malignancy (LPM) | 744 (65.6%) |
| Multiple myeloma | 604 (53.2%) |
| Smouldering multiple myeloma | 23 (2.0%) |
| Plasma cell leukemia | 14 (1.2%) |
| Waldenström’s macroglobulinemia | 46 (4.1%) |
| Solitary plasmacytoma | 16 (1.4%) |
| Amyloidosis | 16 (1.4%) |
| Mature lymphoid neoplasm | 13 (1.1%) |
| LPM, unspecified | 12 (1.1%) |
| MGUS * | 391 (34.4%) |
| MGUS, BM-tested | 124 (10.9%) |
| MGUS, non-BM-tested | 267 (23.5%) |
Data are n (%) or median (range) values. * Monoclonal gammopathy of renal significance (n = 8) and monoclonal gammopathy of neurological significance (n = 10) patients were included. Abbreviations: IFE, immunofixation electrophoresis; MGUS, monoclonal gammopathy of undetermined significance; BM, bone marrow.