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. 2024 Nov 13;25(22):12170. doi: 10.3390/ijms252212170

Figure 10.

Figure 10

The CLSM images illustrate the penetration of porcine skin after treatment with (a) FITC@HMSNs for one hour, (b) LpTW20-FITC@HMSNs for one hour, (c) FITC@HMSNs for six hours, and (d) LpTW20-FITC@HMSNs for six hours. The fluorescence intensity profiles at varying skin depths for (e) Rhodamine B (568 nm) and (f) FITC (488 nm). The cross-sectional CLSM images of (g) hair follicles treated with LpTW20-FITC@HMSNs for six hours, along with the corresponding fluorescence intensity profiles within the hair follicles and the fluorescence intensity profiles across the skin layers for LpTW20-FITC@HMSNs at six hours show (h) red fluorescence from Rhodamine B labeling the particles, (i) green fluorescence from FITC, and (j) a merged image combining (h) and (i) (10× objective lens).