Figure 1.

A. fumigatus ppo mutants exhibit altered susceptibility to CAS, cell-wall-damaging agents, and osmotic stress. The A. fumigatus wild-type and ppo mutants were grown for 5 days at 37 °C in MM that was supplemented or not with CAS 0.25 µg/mL (a), CAS 8 µg/mL (b), CFW 20 µg/mL (c), CR 10 µg/mL (d), and sorbitol 1.2 M (e). The results are expressed as the radial growth of the treatment, divided by the radial growth of the control, and are the average of three biological repetitions ± standard deviation. Statistical analysis was performed using Dunnett’s multiple comparisons test. ** p-value < 0.01, *** p-value < 0.001, **** p-value < 0.0001.