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. 2024 Oct 25;14(11):1371. doi: 10.3390/life14111371

Table 1.

Demographic and clinical characteristics of patients.

Number of Patients (%)
Gender Female 94 (50.8)
Male 91 (49.2)
Stage at Diagnosis IA 76 (41.0)
IB 73 (39.5)
IIA 36 (19.5)
T Stage at Diagnosis T1 88 (47.6)
T2 97 (52.4)
N Stage at Diagnosis N0 82 (44.3)
Nx 67 (36.2)
N1 36 (19.5)
B Stage at Diagnosis B0 180 (97.3)
B1 5 (2.7)
Patch/Plaque Patch 79 (42.7)
Patch + Plaque 106 (57.3)
Morphological Findings Erythematous 120 (64.8)
Hyperpigmented 35 (18.9)
Poikiloderma 13 (7.0)
Folliculotropism 9 (4.8)
PPD-like 7 (3.8)
Hypopigmented 3 (1.6)
GSS 1 (0.5)
Ichthyosiform 1 (0.5)
Pruritus No 77 (41.6)
Yes 108 (58.4)
LDH Levels Normal 170 (91.9)
High 15 (8.1)
β-2 Microglobulin Levels Normal 121 (65.4)
High 64 (34.6)
Eosinophilia No 174 (94.0)
Yes 11 (6.0)
Histopathological Findings Classic 119 (64.3)
Folliculotropism 28 (15.1)
LCT 9 (4.8)
PPD-like 5 (2.7)
GSS 1 (0.5)
Syringotropic 1 (0.5)
Granuloma Annulare-like 1 (0.5)
Immunohistochemical Findings CD4 (+) CD8 (−) 153 (82.7)
CD4 (−) CD8 (+) 28 (15.1)
CD4 (−) CD8 (−) 2 (1.0)
CD4 (+) CD8 (+) 2 (1.0)
CD30 (+) 4 (2.1)
Initial Treatment Type Skin-directed 149 (80.0)
Systemic 6 (3.3)
Combined 30 (16.7)
Initial Treatment Topical Corticosteroid 6 (3.3)
Bexarotene Gel 1 (0.5)
nbUVB 65 (35.1)
PUVA 77 (41.6)
PUVA + Bexarotene Gel 1 (0.5)
Methotrexate (MTX) 2 (1.0)
Acitretin 3 (1.6)
Interferon (IFN) 1 (0.5)
nbUVB + Acitretin 1 (0.5)
nbUVB + IFN 1 (0.5)
PUVA + Acitretin 2 (1.0)
PUVA + IFN 24 (12.9)
PUVA + MTX 1 (0.5)
ECP + IFN 1 (0.5)
Period (Mean)
Age at Diagnosis (Years) 50.8
Age of Onset of Lesions (Years) 45.9
Follow-up Time (Years) 5.6
Time from Appearance to Diagnosis (Months) 56.3

Pigmented Purpuric Dermatosis (PPD); Granulomatous Slack Skin (GSS); lactate dehydrogenase (LDH); Large Cell Transformation (LCT); Narrowband Ultraviolet B (nbUVB); Psoralen Ultraviolet A (PUVA); Methotrexate (MTX); Interferon (IFN); Extracorporeal Photopheresis (ECP).