Table 1.
Number of Patients (%) | ||
---|---|---|
Gender | Female | 94 (50.8) |
Male | 91 (49.2) | |
Stage at Diagnosis | IA | 76 (41.0) |
IB | 73 (39.5) | |
IIA | 36 (19.5) | |
T Stage at Diagnosis | T1 | 88 (47.6) |
T2 | 97 (52.4) | |
N Stage at Diagnosis | N0 | 82 (44.3) |
Nx | 67 (36.2) | |
N1 | 36 (19.5) | |
B Stage at Diagnosis | B0 | 180 (97.3) |
B1 | 5 (2.7) | |
Patch/Plaque | Patch | 79 (42.7) |
Patch + Plaque | 106 (57.3) | |
Morphological Findings | Erythematous | 120 (64.8) |
Hyperpigmented | 35 (18.9) | |
Poikiloderma | 13 (7.0) | |
Folliculotropism | 9 (4.8) | |
PPD-like | 7 (3.8) | |
Hypopigmented | 3 (1.6) | |
GSS | 1 (0.5) | |
Ichthyosiform | 1 (0.5) | |
Pruritus | No | 77 (41.6) |
Yes | 108 (58.4) | |
LDH Levels | Normal | 170 (91.9) |
High | 15 (8.1) | |
β-2 Microglobulin Levels | Normal | 121 (65.4) |
High | 64 (34.6) | |
Eosinophilia | No | 174 (94.0) |
Yes | 11 (6.0) | |
Histopathological Findings | Classic | 119 (64.3) |
Folliculotropism | 28 (15.1) | |
LCT | 9 (4.8) | |
PPD-like | 5 (2.7) | |
GSS | 1 (0.5) | |
Syringotropic | 1 (0.5) | |
Granuloma Annulare-like | 1 (0.5) | |
Immunohistochemical Findings | CD4 (+) CD8 (−) | 153 (82.7) |
CD4 (−) CD8 (+) | 28 (15.1) | |
CD4 (−) CD8 (−) | 2 (1.0) | |
CD4 (+) CD8 (+) | 2 (1.0) | |
CD30 (+) | 4 (2.1) | |
Initial Treatment Type | Skin-directed | 149 (80.0) |
Systemic | 6 (3.3) | |
Combined | 30 (16.7) | |
Initial Treatment | Topical Corticosteroid | 6 (3.3) |
Bexarotene Gel | 1 (0.5) | |
nbUVB | 65 (35.1) | |
PUVA | 77 (41.6) | |
PUVA + Bexarotene Gel | 1 (0.5) | |
Methotrexate (MTX) | 2 (1.0) | |
Acitretin | 3 (1.6) | |
Interferon (IFN) | 1 (0.5) | |
nbUVB + Acitretin | 1 (0.5) | |
nbUVB + IFN | 1 (0.5) | |
PUVA + Acitretin | 2 (1.0) | |
PUVA + IFN | 24 (12.9) | |
PUVA + MTX | 1 (0.5) | |
ECP + IFN | 1 (0.5) | |
Period (Mean) | ||
Age at Diagnosis (Years) | 50.8 | |
Age of Onset of Lesions (Years) | 45.9 | |
Follow-up Time (Years) | 5.6 | |
Time from Appearance to Diagnosis (Months) | 56.3 |
Pigmented Purpuric Dermatosis (PPD); Granulomatous Slack Skin (GSS); lactate dehydrogenase (LDH); Large Cell Transformation (LCT); Narrowband Ultraviolet B (nbUVB); Psoralen Ultraviolet A (PUVA); Methotrexate (MTX); Interferon (IFN); Extracorporeal Photopheresis (ECP).