Table 3.
New terpenoids (208–265) isolated from Fusarium fungi and their biological activities.
| Metabolite Class |
Metabolite Name | Biological Activity |
Fusarium Species |
Fungal Origin |
Ref. |
|---|---|---|---|---|---|
| Sesquiterpenoids | |||||
| Cosmosporasides F–H (208–210) | Antibacterial, cytotoxic, and anti-inflammatory activities | F. oxysporum | Soil-derived fungus | [97] | |
| Cyclonerotriol B (211) | - | F. avenaceum | Soil-derived fungus | [64] | |
| (R,2E,4E)-6-((2S,5R)-5-Ethyltetrahydrofuran-2-yl)-6-hydroxy-4-methylhexa-2,4-dienoic acid (212); (S,2E,4E)-6-((2S,5R)-5-ethyltetrahydrofuran-2-yl)-6-hydroxy-4-methylhexa-2,4-dienoic acid (213) | Cytotoxic activity | F. tricinctum | Plant endophytic fungus | [98] | |
| Fusanoids A–G (214–220) | Cytotoxic activity | Fusarium sp. | Plant endophytic fungus | [99] | |
| Fusarane B (221) | Cytotoxic activity | F. graminearum | Plant pathogenic fungus | [88] | |
| Fusarchlamols A–F (222–227) | Antifungal activity | Fusarium sp. | Plant endophytic fungus | [100] | |
| HT2-3-O-α-glucoside (228); HT2-4-O-α-glucoside (229) | - | F. sporotrichioides | Plant pathogenic fungus | [101] | |
| 3β-Hydroxy-β-acorenol (230) | - | F. proliferatum | Plant endophytic fungus | [64] | |
| 8-(2-Methylbutyryl)-neosolaniol (231) | - | F. sporotrichioides | Plant endophytic fungus | [102] | |
| Microsphaeropsisins D (232) and E (233) | Antifungal activity | F. lateritium | Insect-derived fungus | [103] | |
| Proliferacorins A–M (234–246) | - | F. proliferatum | Soil-derived fungus | [104] | |
| Tricinolone (247); tricinolonoic acid (248) | - | F. graminearum | Plant pathogenic fungus | [96] | |
| Diterpenoids | |||||
| 3β,16α-Dihydroxy-9,15-cyclo-gibberellin A9 (249); 7α-methoxy-6,7-lactone-gibberellin A12 (250); 7β-methoxy-6,7-lactone-gibberellin A12 (251); 16α-hydroxy-9-ene-gibberellin A14 (252) | Promoting effect on seedling growth | Fusarium sp. | Plant endophytic fungus | [105] | |
| Fusarium acids A–H (253–260) | Inhibition of hypocotyl and root elongation in tomato seedlings | F. oxysporum f.sp. radicis-lycopersici | Plant pathogenic fungus | [106] | |
| Triterpenoids | |||||
| Integracide K (261) | Cytotoxic activity | F. armeniacum | Plant endophytic fungus | [107] | |
| Integracide L (262) | Lipoxygenase inhibitory activity | Fusarium sp. | Plant endophytic fungus | [108] | |
| Others | |||||
| (E)-9,10-Dihydroxy-2,6,10-trimethylundec-5-enoic acid (263); (E)-8,9-dihydroxy-1-methoxy-5,9-dimethyldec-4-en-2-one (264) | - | Fusarium sp. | Plant endophytic fungus | [28] | |
| Fusariumin C (265) | Antibacterial activity | F. oxysporum | Plant endophytic fungus | [78] | |