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. 2024 Nov 13;29(22):5341. doi: 10.3390/molecules29225341

Scheme 4.

Scheme 4

Synthesis of thiadiazole and other azole-hybrid scaffolds (A,B) and biological profiles (C) of the most promising ones. (HepG2: hepatic carcinoma cells; MCF-7 and MDA-MB-231: breast cancer cells; HCT-116: colon cancer cells; PC3: prostate cancer cells; L-929: non-cancerous fibroblast cells; Paz: pazopanib; Dox: doxorubicin; Sor: sorafenib).