ACACA |
cytosolic acetyl-CoA carboxylase |
ACC |
acetyl-CoA carboxylase |
Acot3 |
acyl-CoA 3 thioesterase |
ALT |
alanine aminotransferase |
AST |
aspartate aminotransferase |
Atg |
autophagy-related proteins |
BAs |
bile acids |
CAT |
catalase |
ChREBP |
carbohydrate response element-binding protein |
COX |
cyclooxygenase |
CPT-1α |
carnitine palmitoyltransferase 1-alpha |
CRP |
C-reactive protein |
CYP |
cytochrome P450 |
DGAT2 |
diacylglycerol acyltransferase 2 |
DNL |
de novo lipogenesis |
ER |
endoplasmic reticulum |
FABP |
fatty acid-binding protein |
FABP1 |
fatty acid binding protein 1 |
FAS |
fatty acid synthase |
FATP5 |
fatty acid transporting protein 5 |
FDA |
Food and Drug Administration |
FFAs |
free fatty acids |
FOXA1 |
forkhead box A1 protein |
FXR |
farnesoid X receptor |
GGT |
glutamate aminotransferase |
GI |
gastrointestinal |
GM |
gut microbiota |
GSH |
glutathione |
HDL |
high-density lipoproteins |
HFD |
high-fat diet |
HO-1 |
heme oxygenase-1 |
HSCs |
hepatic stellate cells |
HT |
hypertension |
IFN |
interferon |
IL |
interleukin |
iNOS |
induced nitric oxide synthase |
IR |
insulin resistance |
IRS |
insulin receptor substrate |
LDs |
lipid droplets |
LOX |
lipoxygenase |
MASH |
metabolic dysfunction-associated steatohepatitis |
MASLD |
metabolic dysfunction-associated steatotic liver disease |
MetS |
metabolic syndrome |
NAFLD |
non-alcoholic fatty liver disease |
NASH |
non-alcoholic steatohepatitis |
NE |
neutrophil elastase |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
PGC-1α |
proliferator-activated receptor gamma coactivator 1-alpha |
PINK1 |
PTEN-induced putative kinase 1 |
PON2 |
paraoxonase 2 |
PPAR |
peroxisome proliferator-activated receptor |
PUFAs |
polyunsaturated fats |
QE |
quercetin |
ROS |
reactive oxygen species |
SASP |
senescence-associated secretory phenotype |
SCFAs |
short-chain fatty acids |
SHP |
small heterodimer partner |
SIRT |
sirtuin |
SOD |
superoxide dismutase |
SREBP-1c |
sterol regulatory element-binding protein 1c |
T2DM |
type 2 diabetes mellitus |
TG |
triglycerides |
TGFβ |
transforming growth factor beta |
TGR5 |
takeda G protein-coupled receptor 5 |
TLR4 |
toll-like 4 receptor |
TNF-α |
tumor necrosis factor-alpha |
TXNIP |
thioredoxin interacting protein |
VLDL |
very-low-density lipoprotein |
WAT |
white adipose tissue |
WC |
waist circumference |