β-emitter with g 113, 208 keV
LET 0.5 MeV, 0.2 keV/μm
Range 2 mm (crossfire effect)
Half-life 6.7 days
>50% PSA decline rate of 46% **
Adverse event: resistance, sialadenitis, less nephrotoxicity
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α-emitter with 4a, and g 440 keV
LET 5.8 MeV, 100 keV/μm
Range 40–100 μm (by-stander effect)
Half-life 9.9 days
>50% PSA decline rate of 60% **
Adverse event: sialadenitis, more nephrotoxicity
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