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. 2024 Nov 10;16(11):1430. doi: 10.3390/pharmaceutics16111430

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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GO and KEGG enrichment analysis on the target genes of differently expressed miRNAs. (A) The GO analysis indicated that up-regulated miRNAs in the 14d-EVs group were primarily associated with biological processes like the Notch signaling pathway and the positive regulation of cell motility and movement. (B) The KEGG pathway bubble plot illustrates that the target genes of differentially expressed miRNAs were predominantly enriched in pathways related to osteogenic differentiation. (GO: gene ontology. KEGG: Kyoto Encyclopedia of Genes and Genomes).