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. 2024 Nov 14;16(22):3882. doi: 10.3390/nu16223882

Figure 4.

Figure 4

Effect of PDREP on the osteoarthritis score and the change of weight-bearing in MIA-induced OA rats. The 60 SD rats were divided into six groups (10 rats per group) and were orally administered treatments for six weeks: normal control group (Normal), MIA-induced OA group (Control), MIA injection + PDREP 100 mg/kg group (PDREP 100 mg/kg), MIA injection + PDREP 300 mg/kg group (PDREP 300 mg/kg), MIA injection + PDREP 500 mg/kg group (PDREP 500 mg/kg), and MIA injection + MSM 300 mg/kg group (MSM 300 mg/kg). In the 3rd week of sample administration, MIA was injected to induce arthritis. (A) Osteoarthritis score was evaluated once every 3 or 4 days. (B) The index of weight-bearing (weight of induced lower extremity/weight of normal lower extremity × 100). Bars labeled with different superscript letters indicate p values < 0.05. Data are expressed as mean ± SE (n = 10).