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. 2024 Nov 18;17(11):1549. doi: 10.3390/ph17111549

Table 1.

Criteria for cyclic vomiting syndrome and cannabinoid hyperemesis syndrome.

Cyclic Vomiting Syndrome (CVS) Cannabinoid Hyperemesis Syndrome (CHS)
  • Stereotypical episodes of vomiting acute in onset

  • At least three discrete episodes in the prior year and two episodes in the past six months, occurring at least one week apart

  • Absence of vomiting between episodes, but other milder symptoms can be present between cycles

  • Criteria fulfilled for the last three months with symptom onset at least six months prior to diagnosis

  • Symptoms present for past three months with onset at least 6 months prior

  • Stereotypical episodes lasting <one week

  • At least 3 episodes in last one year and 2 episodes in last six months (occurring at least one week apart)

  • No vomiting between episodes

  • Milder symptoms can be present during this

  • All these criteria should be associated with chronic use of cannabis and stop after its cessation