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. 2024 Nov 11;17(11):1516. doi: 10.3390/ph17111516

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of PV extract on the apoptosis of prostate cells in a rat BPH model. (A) Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining (magnification, ×400). (B) As a percentage, the count of TUNEL-positive cells. (C) Cleaved caspase-3 expression in prostate tissue. NC, PBS- and corn oil- dispensed rats; BPH, PBS- and testosterone-dispensed rats; BPH + FIN, testosterone- and finasteride-dispensed rats; BPH + PV60, testosterone- and PV 60 mg/kg-dispensed rats; BPH + PV80, testosterone- and PV 80 mg/kg-dispensed rats. Representation of results as average ± SD. Comparison ## p < 0.01 with the NC group; comparison ** p < 0.01 with the BPH group.