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Cannabidiol oil mitigates reactive oxygen species (ROS) production and enhances antioxidant expression. (A) ROS production measured with H2DCFDA. (B) mRNA expression of heme oxygenase 1 gene (HMOX1) and superoxide dismutase 2 (SOD2). (C) Protein contents of catalase, heme oxygenase 1 (HO-1), SOD1, and SOD2. CON: untreated Caco-2 cells; CBD: Caco-2 cells treated with 10 µM cannabidiol (CBD) oil. Mean ± SEM, n = 4, *: p ≤ 0.05; **: p ≤ 0.01.
