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. 2024 Nov 9;16(22):3843. doi: 10.3390/nu16223843

Figure 6.

Figure 6

Pure cannabidiol induces phosphorylation of AMPK and upregulates both mitochondrial and antioxidant signaling. (A) Protein contents of p- AMP-activated protein kinase (AMPK), t-AMPK, and sirtuin3 (SIRT3). (B) Protein contents of catalase and heme oxygenase 1 (HO-1). (C) mRNA expression of NAD(P)H quinone dehydrogenase 1 (NQO1) and superoxide dismutase 2 (SOD2). CON: untreated Caco-2 cells; CBD: Caco-2 cells treated with 10 µM cannabidiol (CBD). Mean ± SEM, n = 4, *: p ≤ 0.05; **: p ≤ 0.01.