Table 5.

Various forms of chewable tablets as reference drugs.

Pharmaceutical Tests	API	Comparison	Reference
in vivo	pyrantel	either to swallow whole, to chew and swallow, or to swallow previously pulverized tablets	Wesche 1994 [6]
	raltegravir	administered after crushing	Krogstad 2021 [7]
	albendazole	crushed to a fine powder by mortar and pestle	Sawatdee 2019 [8]
	montelukast	intact chewable tablet with 240 mL water	Cánovas 2011 [9]
	montelukast	chewable tablet with warm water 240 mL	Zhu 2023 [10]
	montelukast	chewable tablet with 240 mL water	Zaid 2015 [11]
	sildenafil	chewable tablet with 50 mL water	Yoo 2017 [12]
	sildenafil	chewed until full disintegration and then swallowed with or without 250 mL water	Valenzuela 2011 [13]
	sildenafil	chewed and immediately swallowed	Marcelín-Jiménez 2012 [14]
	montelukast	intact chewable tablet	Knorr 2010 [15]
in vitro dissolution	verapamil	whole tablet, crushed tablet using a commercial tablet crusher, or tablet chewed in the mouth and then expelled into dissolution fluid	El-Gazayerly 2004 [4]
	lanthanum carbonate	whole tablet, crushed tablet, or the tablet fraction of less than 200 μm	Yang 2013 [3]
	montelukast	intact chewable tablet compared to ODT	Chen 2015 [16]
	albendazole	intact chewable tablet	Sawatdee 2019 [8]
	albendazole	intact chewable tablet	Kimaro 2019 [17]
	ciprofloxacin	intact chewable tablet	Usmani 2023 [2]