Table 3.
(A) | |||
---|---|---|---|
Beta | 95% CI | p Value | |
MASLD (yes vs. no) | −2.5 | (−5.6, 0.5) | 0.105 |
MASH (yes vs. no) | −3.4 | (−6.3, −0.4) | 0.025 |
Liver fibrosis (yes vs. no) | −2.4 | (−5.6, 0.7) | 0.129 |
Liver fibrosis ≥ F2 (yes vs. no) | −4.3 | (−8.7, 0.1) | 0.053 |
Age (years) | −0.39 | (−0.55, −0.23) | <0.001 |
Sex (female vs. male) | −0.57 | (−3.77, 2.64) | 0.728 |
Baseline weight (kg) | 0.07 | (0.01, 0.14) | 0.029 |
Baseline BMI (kg/m2) | 0.16 | (−0.06, 0.39) | 0.152 |
Baseline diabetes (yes vs. no) | −4.5 | (−7.5, −1.6) | 0.003 |
Baseline HbA1c (%) | −1.5 | (−2.9, −0.1) | 0.039 |
Baseline hypertension (yes vs. no) | −3.0 | (−6.0, −0.1) | 0.046 |
Baseline triglycerides (mg/dL) | −0.02 | (−0.01, 0.04) | 0.073 |
Baseline AST (U/L) | −0.03 | (−0.13, 0.08) | 0.598 |
Baseline ALT (U/L) | 0.03 | (−0.05, 0.11) | 0.460 |
(B) | |||
Beta | 95% CI | p Value | |
MASLD (yes vs. no) | −8.3 | (−15.3, −1.3) | 0.021 |
MASH (yes vs. no) | −11.4 | (−18.1, −4.7) | 0.001 |
Liver fibrosis (yes vs. no) | −10.4 | (−17.6, −3.2) | 0.005 |
Liver fibrosis ≥ F2 (yes vs. no) | −13.5 | (−23.5, −3.5) | 0.008 |
Age (years) | −0.64 | (−1.00, −0.26) | 0.001 |
Sex (female vs. male) | −0.99 | (−8.40, 6.42) | 0.793 |
Baseline weight (kg) | −0.17 | (−0.31, −0.02) | 0.030 |
Baseline BMI (kg/m2) | −1.07 | (−1.57, −0.58) | <0.001 |
Baseline diabetes (yes vs. no) | −8.9 | (−15.9, −2.0) | 0.012 |
Baseline HbA1c (%) | −4.4 | (−7.7, −1.2) | 0.008 |
Baseline hypertension (yes vs. no) | −4.0 | (−10.9, 2.9) | 0.253 |
Baseline triglycerides (mg/dL) | −0.03 | (−0.08, 0.02) | 0.206 |
Baseline AST (U/L) | −0.12 | (−0.37, 0.13) | 0.341 |
Baseline ALT (U/L) | −0.01 | (−0.20, 0.18) | 0.937 |
CI, confidence interval; MASLD, metabolic dysfunction-associated steatotic liver disease; MASH, metabolic dysfunction-associated steatohepatitis; BMI, body mass index; HbA1c, glycated hemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase. Beta values denote the coefficient of the general linear model.