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. 2024 Nov 8;16(11):483. doi: 10.3390/toxins16110483
·OH hydroxyl free radicals
4-HNE 4-hydroxy-2-nonenal
8-OHdG 8-hydroxydeoxyguanosine
ADME absorption, distribution, metabolism and excretion
AFAR aflatoxin aldehyde reductase
AFB1 aflatoxin B1
AFB1-GSH aflatoxin B1-glutathione
AFBO AFB1-exo-8,9 epoxide
AFB1 III 2,3-dihydro-2-(N-formyl-2,3,6-triamino-4-oxopyrimidine-N-yl)-3-hydroxy AFB1
AFB1-Cys-Gly aflatoxin B1-Cysteine-Glycine adduct
AFB1-dhd AFB1-dihydrodiol
AFB1-FAPY AFB1-formamidopyrimidine
AFB1-N7-Gua 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-AFB1
AFB2 aflatoxin B2
AFB2a aflatoxin B2a
AFB3 aflatoxin B3
AFBO aFB1-exo-8,9 epoxide
AFG1 aflatoxin G1
AFG2 aflatoxin G2
AFG2a aflatoxin G2a
AFGM1 aflatoxin M1
AFGM2 aflatoxin GM2
AFGM2a Aflatoxin GM2a
AFL aflatoxicol
AFL H1 aflatoxicol H1
AFL M1 aflatoxicol M1`
AFM1 aflatoxin M1
AFM1-P1 4,9a-dihydroxyaflatoxin B1
AFM2 aflatoxin M2
AFP1 aflatoxin P1
AFQ1 aflatoxin Q1
AFQ2a aflatoxin Q2a
AMAs anti-mycotoxin additives
AUC area undet the curve
Bax Bcl-2-associated protein x
Bcl B-cell leukemia
BER base excision repair system
C18 octadecyl
CAT catalase
CBH cutaneous basophil hypersensitivity
CL clearance
Cmax maximum plasma concentration
CMI cell-mediated immunity
CYP450 cytochrome P450 system
DNA deoxyribonucleic acid
DON deoxynivalenol
EAC East African Community
EGM esterified glucomannan
EPHX epoxide hydrolase
ETs extracellular traps
EU European Union
ELISA enzyme-linked immunosorbent assay
cELISA competitive enzyme-linked immunosorbent assay
FAO Food and Agriculture Organization of the United Nations
FB1 fumonisin B1
FDA Food and Drugs Administration, United States of America
GIT gastrointestinal tract
GPX glutathione peroxidase
GSH glutathione
GSTs glutathione-S-transferases
H2O2 hydrogen peroxide
HBV hepatitis B virus
HCC hepatocellular carcinoma
HI humoral immunity
HPLC high performance liquid chromatography.
HPTLC high-performance thin layer chromatography
HSCAS hydrated sodium calcium aluminosilicates
IFN-γ interferon-gamma
IL-10 interleukin 10
IL-6 interleukin 6
KEBS Kenya Bureau of Standards
kel elimination rate constant
LADME liberation, absorption, distribution, metabolism and excretion
LC liquid hromatography
LC-MS liquid chromatography-mass spectrometry
LC-MS/MS liquid chromatography–tandem mass spectrometry
LPO lipid peroxidation
MDA malondialdehyde
MIPs molecularly imprinted polymers
m-RNA messenger ribonucleic acid
MS mass spectrometry
NATs acetyltransferases
NER nucleotide excision repair system
NO nitric oxide
O2-, superoxide anion
OS oxidative stress
OTA ochratoxin A
8-OHdG 8-hydroxydeoxyguanosine
p53 gene protein 53 gene
PHS prostaglandin H synthase
QuEChERS quick, easy, cheap, effective, rugged, and safe
RNS reactive nitrogen species
ROS reactive oxygen species
SEA South-East Asia
SOD superoxide dismutase
SPE solid-phase extraction
SSA sub-Saharan Africa
SULTs sulfotransferases
TLC thin-layer chromatography
Tmax time it takes for a toxin to attain maximum concentration in circulation
UDP uridine 5′ diphosphate
UGTs uridine 5′ diphosphate –glucuronosyltransferases
UHPLC ultra high performance liquid chromtography
UV ultraviolet
vd volume of distribution
WHO World Health Organisation
ZEA zearalenone
RS reactive species
USA United States of America
PUFAs polyunsaturated fatty acids