Table 5.

Inter-center comparison of vasopressor use analyzed by opioid exposure categories (N = 120).

Adjusting for center
Variable	Odds ratio	95% confidence limits		p-value
High vs. low cumulative opioid dose	1.19	0.44	3.2	0.735
Center 2 vs. Center 1	6.1	2.12	17.52	0.001
Center 3 vs. Center 1	2.25	0.81	6.2	0.119
Center 3 vs. Center 2	0.37	0.13	1.03	0.056
Adjusting for center and EEG-confirmed seizure
Variable	Odds ratio	95% confidence limits		p-value
High vs. low cumulative opioid dose	1.31	0.47	3.65	0.605
Center 2 vs. Center 1	6.53	2.21	19.26	0.001
Center 3 vs. Center 1	1.8	0.62	5.25	0.282
Center 3 vs. Center 2	0.28	0.09	0.82	0.021
EEG-confirmed seizure	2.72	0.98	7.58	0.056